Investigation of Anaemia

Measurement of vitamin B12, folate, red cell folate, ferritin, gastric intrinsic factor antibodies (GIFAB) and erythropoietin are all routinely available.

View 2011 guidelines for the diagnosis and management of iron deficiency in pregnancy.

Sample requirements: B12 & folate - 4 mL SST (Gold capped) tube, Ferritin - 4 mL SST (Gold capped) tube, RBC Folate- 3ml EDTA (Purple capped) tube.  A separate sample for Chemistry is no longer required, we can do all the tests from the same sample providing the sample is adequately filled.

Reasons for referral for bone marrow investigation

  1. Diagnosis of haematological malignancy
  2. Staging of lymphomas and Hodgkin's disease
  3. Suspected marrow infiltration by cancer as suggested by a leucoerythroblastic blood film

Note that in all cases a marrow examination is part of a full clinical and laboratory appraisal and should be discussed with a clinical haematologist.

Page updated: 14/07/17 | Updated by: Michael 0'Sullivan

Investigation of Anaemia Links