Anti-D Prophylaxis (RAADP)

Anti-D immunoglobulin for Rh(D) prophylaxis is available from the Bloodbank on each site for any Rh(D) Negative woman who has had a potentially sensitising episode, in accordance with current national guidelines.

Routine Antenatal Anti-D Prophylaxis (RAADP)

1500 iu (300mg) Rhophylac anti-D has been offered to all Rh(D) Negative pregnant women in the Leeds and Bradford area (NICE guidelines - 2002) since April 2005. The Rhophylac immunoglobulin is administered at the 28 week antenatal check held at the LGI, SJUH and BRI Antenatal Clinics. Rh(D) negative women should be referred to the relevant clinic via their midwife. The 28 week blood grouping sample should be taken prior to the administration of Rhophylac to prevent interference with the antibody screen.

Please bear in mind that:

  • Rh(D) Negative women should still be given a stat dose of anti-D if they have a further sensitising episode.
  • Anti-D prophylaxis is inappropriate for women who have formed immune anti-D.

Back to Antenatal Testing


Page updated: 16/11/16 | Updated by: Reg Rabett

Anti-D Prophylaxis (RAADP)