November 18, 2017
Conditions that may be associated with vitamin deficiency Minimize

Conditions that may be associated with vitamin deficiency

Many vitamin deficiencies remain undetected in view of the difficulty in measurement and also the speed with which trials of therapy can give a definitive answer. However, the signs of classical deficiency may not be apparent in all clinical situations eg where vitamins play a preventative role, and in severe illnesses (unrelated to vitamin deficiencies) where the anti-oxidant vitamins may be rapidly consumed by the disease itself.

Clinical condition

vitamin deficiency

Alcoholism

B1, B2, B6, B12, folic acid, C

Poor diet

B1, B2, B12, folic acid, C

Malabsorption i) fat malabsorption

A, D, E, K

Malabsorption ii) structural disease

B2, B12, folic acid

Pregnancy

B2, B6, B12, folic acid

Post gastric surgery

B12

Critically ill patients

C E

Renal disease
 on dialysis

D, folic acid
 additional B1, C

Osteomalacia / rickets

D

Liver disease

A, D, E, K

Pancreatic failure

A, D, E, K

Cardio-respiratory disease
 diuretic unresponsive CCF

D
B1

Pernicious anaemia

B12

Cerebellar ataxia

E

Long term hospital inpatients

 D +.....

Increased vitamin requirements due to drug therapy

Isoniazid

Niacin, B3, B6

Penicillamine

B6

Anticonvulsant (long term)

Biotin, B2, B6, D, folic aid

Metformin

B12

Neomycin (long term)

B12

Phenytoin

Folic acid, D

Orlistat

A, D, E, K

Methotrexate

Folic acid

  

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