May 27, 2020
Water Deprivation Test 3: DDAVP Test Minimize

Water deprivation test 3: DDAVP Test


Administer DDAVP 2 microgram im
Measure urine volume and osmolality at hourly intervals for at least 3 hours.

Fluid should be restricted to less than 500 mL in the 8 hours after the test


This test is contraindicated in patients with heart failure and ischaemic heart disease


see Water Deprivation Test #1

Sensitivity and Specificity

see Water Deprivation Test #1


  • Thompson CJ. Polyuric states in man. Clin Endocrinol Metab 1989;3:473-497.
  • Miller M, Dalakos T, Moses AM, Fellerman H, Streeten DHP. Recognition of partial defects in antidiuretic hormone secretion. Arch Intern Med 1970;73:721-729.

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